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Anti-PSA-NCAM MicroBeads, human, mouse, rat
- 类型：细胞分选试剂盒
- 品牌：Miltenyi
- 种属：Mouse,Rat,Human
规格: for 5×10E8 total cells
货号: 130-092-966
价格: ¥9286.34
优惠: ¥7243.00
Overview
Anti-PSA-NCAM MicroBeads have been developed for the positive selection or depletion of PSA-NCAM+ cells from tissue or cell culture.
Background information
Anti-PSA-NCAM MicroBeads recognize polysialic acid (PSA), which is linked to the extracellular domain of the neural cell adhesion molecule (NCAM, CD56). PSA-NCAM, the highly polysialated form of NCAM, is predominantly expressed in embryonic and neonatal neural tissue. In adult mammalian brain PSA-NCAM expression is restricted mainly to areas that retain neurogenic potential, such as the subventricular zone (SVZ) and the dentate gyrus of the hippocampus. PSA-NCAM is a marker for immature neuronal-committed progenitors that are permanently generated in the SVZ and migrate along a well-defined pathway, the rostral migratory stream, into the olfactory bulb where they differentiate into GABAergic and dopaminergic interneurons. PSA-NCAM positive neuronal precursors have been isolated from rat forebrain and from mouse SVZ tissue after depletion of A2B5+ glial progenitor cells.
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▪ ImunoSep buffer（货号#604025/604050）
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数据：
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图1 用神经组织解离试剂盒(T)、抗PSA-NCAM微珠、MiniMACS™ Separator和MS柱分离从P1小鼠全脑组织衍生的单细胞悬浮液中分离。 用大鼠抗小鼠的IgM-APC荧光染色，流式细胞仪分析细胞。
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